Treatment of hepatitis Delta

treatment of chronic delta hepatitis

Treatment of Chronic Delta Hepatitis

Please cite this paper as: Rizzetto, M. Treatment of Chronic Delta Hepatitis. Hepat Mon. 2011;11(9):701-2. DOI: 10.5812/kowsar.1735143X.759 Implication for health policy/practice/research/medical education: Delta Hepatitis treatment is a controversial issue. There are a few randomized, double blind, controlled studies on HDV treatment. Up to now, α-INF is the only confirmed medicine by FDA to h...

treatment of chronic delta hepatitis: a nine-year retrospective analysis

Construction and Eukaryotic Expression of Recombinant Large Hepatitis Delta Antigen

Background: Hepatitis delta virus (HDV) is a subviral human pathogen that exploits host RNA editing activity to produce two essential forms of the sole viral protein, hepatitis delta antigen (HDAg). Editing at the amber/W site of HDV antigenomic RNA leads to the production of the large form (L-HDAg), which is required for RNA packaging. Methods: In this study, PCR-based site-directed mutagen...

Treatment of chronic hepatitis delta with pegylated interferon-α2b

Background/Aims: Chronic hepatitis D is difficult to treat. The present pilot study investigated the efficacy and tolerability of pegylated (PEG)-interferon (IFN)-a2b in chronic hepatitis D. Patients and Methods: Twelve patients with chronic hepatitis D were prospectively treated with 1.5 mg/kg PEG-IFN-a2b for 48 weeks and followed for 24 weeks. Sustained response (SR) was defined as undetectab...